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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'debd203ad1b53bcdf18bff7811a5d27e9e20d0ea4f1e4f9c6de9d4639e0fb344' 
  AND token = '4Y2D7c/DEiWd3/K105b7Ak1AGCn+V+ZmRaTX1TUhRns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}