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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf74c5f19f7133fb70b60928923bcb09024d70bbbf506f1167613cf3af11a11' 
  AND token = '1xs8VP8JGmU+r4tfs9rf8jEDaWHaxhz0btWaCcaH68Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}