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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7e20387c2526c9a35b4be33ee4f9ae5dd117fa22c207abc9bc79d56df3ee1a' 
  AND token = 'QCA4eBQ1wXLOB8w81dBb1W0sC1FyF+XRz+RO+qfbLGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}