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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22dc57314ce35d55dc507ce2d20488dec88511d84baf1eb66de5b26c7c38caa' 
  AND token = 'Q4T+8+3vMneg2S8yhb6utnGDqqHJVfTQqyto9uowSGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}