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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4908e92429acc160fcf9817adb21603ddc6146015f74667123ae9a653776792' 
  AND token = 'NVZoMh1y0P8d9nL3D5rTonUKS9qyL+3xI2IxT9rj7hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}