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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0c533eafc5627dbb35836f102308fccc4f14cc6bba3bedb03b12133e093390' 
  AND token = 'krWQjlHdsJ4nXRsh5uSOPRWB9ZwZnpmyIQD4AB9/zRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}