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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0823cc3f7ec295db0abc27fb9760d1dbecb0342a74e01e81721710b23710e9b4' 
  AND token = '9IMKt2S/evHCrbCJpt47oqr+hjkuKOx27CrHC2JJ/48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}