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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8954613e40d6cbb48e13bfd6f6c191b81aee6a4d053dc781224a4cb7f9a2cd7' 
  AND token = 'IPuxdapjh5sLkQgtPwEPq7DRZpfRIEk5KPhPyygq1+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}