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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2148baee1cdc6ac65ea6b8fcf68355e5d79446d8545fd9da54c1ba046f69b6d' 
  AND token = 'WzgWm3KH6UO452phuwOPxJNch98mMiVgRLB5p/2wbUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}