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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6747e8f23f38915e1668ccc6e38e7f59b460126d2a11cee2b6757c0e1061ed05' 
  AND token = 'Zzm63u7pQSMLtYcsBNY1QYZ4RBaOV7yX3Ak1jJ/ghkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}