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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0de8a5855fb60cc00831d57b0c6391725022468a3592478b0ae16c2bd8ce65' 
  AND token = 'd8G2oSLvFTjmzBxpm5LlaH+NlFOiOKJhMJmD7xNB2qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}