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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23c552d0fd097c6d9bc4610409c623b4b6eb637204cc914bf3f06f7b0c5b8478' 
  AND token = 'JKjpui2pKxmpqCa6AfcNcV35oRgle9s8QLZMPx2qdHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}