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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365739d28098a01c65a6b0b0321f8ae6b10f0fa37d559f2ae3476d7840394dc5' 
  AND token = 'rEf7Ckizh7Wjr5fk+F/sdgE6nTgJRS6OQ463dvzI6nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}