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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d3bdc1bbe1bed19ae4209692ff0440f813562d8e5d64a1d6c671c707d08910' 
  AND token = 'qEzHhuGhbIGU/RY3W85BmlLddSc83BPQNf3Ed0ZXRWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}