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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e10ee30533b3cbd5d7f35be88ccb0bdd5167a6fac1e278891a1bc1bed9d2411' 
  AND token = 'JjifL7f+/sY9Y3sqN4P+1O0HRH2auoI3hZTwBeVPt64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}