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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e2033ac97842378b6761d9be72edaafc42ecc1bcdc15bb446469b20c3d2e67' 
  AND token = 'kc/XqFHT87iyGVc6NmLffi2L3B3vFjQYgHa2Tz2y5Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}