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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228ca9ea48f3554c1069bf9a838de27656824e7c5f9976bea28bb83582db4a59' 
  AND token = '3EQszqz+zd2tvA02F3wQwNp+vZTSuebZ4ZFrINwQe9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}