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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46397b343aec829c14cb3a58001005611a913e2c280cfd99f5b72cbe4add0f6d' 
  AND token = 'NWdyK4XCTP1LQuEl0yo0sg4qqbhLlJvLo279ns5kO48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}