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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c52b1d5fb380a2f658db9c531b211ff3aaa51d6671e7c622ecde3af02f4458' 
  AND token = 'Xtq7W2gP7UOy+hplVMSm+ZL2bDlouHpsUtNbPY84E8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}