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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead03d4cddc6c9104f9e89544d30d337f589f10e61eba3647865d4ae14ada43c' 
  AND token = 'amI5Kk300nuv5Uek+YvvftB4vYW3wiS43U5b4GowTF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}