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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc38d80236d3ed1cc3c363fdc892b4a224b59f0a49040a9ff73293c5508fdb9' 
  AND token = 'CpNgTtqI5rUFO4jkbtXUl3hYuDjU1pYWLW/AlqcA9Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}