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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5625a6c4a6ced03602026f0f995dbf285117967e9ac25ea92a4150966ee6cba6' 
  AND token = '7ldjJuOJOjxXv3oNFB+PY449/aUyueRKrsKW6VWGCrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}