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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89cf37e5021ede5e26ce971cac5a1ca27d1c770ff434a96246931d58a591148' 
  AND token = 'bi5hic1TYuX1sf+clsAaE3/7tNxNOHlvAbe+sHYUfb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}