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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4edefd4cb951bc742a1841be956f4e841c178bbe35b8d1ca8d062443ca0e54' 
  AND token = 'ltq4Dkm+cfRvtg2kNH+LUT4uBm1xjd3X7qirDg5qRxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}