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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85cdb0cb46e54f6492eab9a4dffb124dbc003cdeed5d4c6f74e64bcc142c4cb4' 
  AND token = 'nYaZYBx4Tc/JOQlEc9yqycfCZAQAH+01dUV6J9ZTIsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}