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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c64b5707c6b0097a06c46ae182a35fd74f00f25a68a65fb8940e767ea98c513' 
  AND token = 'JEXbA7fA9lPZ3tF7NhssFck7Fyx2IJmuH/1wudwh0tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}