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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6927162b8ec260cbd37015d5b9bac3d976d5e907fa5735f45de92c28e6dae6' 
  AND token = 'hmu9541US1hE0HTVVv6ZHdHUJL0VynDUvQURci55jQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}