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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a15afcc9c95fd65c99c81abeed0cdbc6183877159efdaf6763dc41c84af896' 
  AND token = '3zZx1nO2LENRufux7l1UFH+KytZtnuI1TgVG2HnDe2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}