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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a40d2490d826e85a74553ae129bf68c271146428a5d8618be77ae29b8c4775' 
  AND token = 'kxv9V4PJQydUQkwxQNk3aDl+DW9FyqXEmnCdTgjKxTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}