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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af33feb69dcd6049d45b067328f967d67a40cf784fe25c66f396df2038955dd8' 
  AND token = 'Bq6nSUgovjsiZZlF8lutuonPW8xp1s/uSpJcPB8ip5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}