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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e112f08246542a0708fa095844fbd8020daa245da465d3005006a2fdea8e4b79' 
  AND token = 'SMaHEtiT4qMi9j0So76+B1qrlq+TiOoidpW6GxcWl70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}