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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0250d2210f9ff64a1f566d62d4d47e7ca3fd0380e7ee0fc85102ebb4a5a30cb1' 
  AND token = 'oeZj7VhOyrrIOdW6BgAeLH+01r3M8Fz8iM4ia0PmM/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}