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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37839f4342ce880c06759d6da130360593fcfa004b30968924954cf250b31869' 
  AND token = 'Or7M/bgbupyaY8T4nO+5xmeObOf5GnxJBiz4a1UUa7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}