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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66855dcc1d393c7faafc21e44c0c736c6f549517bb0c891d26f950fcdc6c519' 
  AND token = 'bIHrvVA/8nbfZZ+a1yOkQf2kxnYQGyeyE0bnk2P0dys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}