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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a27fb7d647f531c72e0d2852acb868a51e5dea08347c5c36502eb88966fb0ed' 
  AND token = 'zG+NhL6hO1TAeYCYSxM1xhUNjBPgMBmz1DL6MX1+jek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}