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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8fc4dc6e3737637e0e33be54291dad28b0698fb20fd9445f2d51b70746b90d' 
  AND token = 'GmPyDjFIiOXtZyBgw7oPuTfAbtWpVTO8o5rDtDypOT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}