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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0283e86c638f2a6dee781c3b1a80acc2c1e4aba219fe8026779a024e2bb753' 
  AND token = 's1H6zTXMkl85wqjDGGhlkr3L5OWysxQQpjcIR0kpUs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}