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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60f91e29e0fdb57ee642b6970cf988b3439d57279faece0713ef4319623e33f2' 
  AND token = 'A2y5UtOiMHAN2wUehyTwl3rlHVoHE8N18AFuB6xkCQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}