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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e750961aa0b698162bb3c158ef408af092d850e768b5f4c2e1108e59ca5447f1' 
  AND token = 'z4r9gLWxOei1Iyel6uAbOgG7Ifsbcwe8JJocoOlLvYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}