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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35efcace9f4d6a8fdb77147a40e360afa285bb17bfcf23cbefbde2dfb168d346' 
  AND token = 'AaxrNotQsgI74wfQaqmpbG6LNrDgfB+wgWXDcapqWiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}