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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff0b41deb2e8a2225285be325c85b469b98e126ad89ba7c6c511c0fbb813d52' 
  AND token = 'm/PwMevmOHiTYneFf7EPuE7rSmJRpakkwVYPhjnigrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}