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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8ecef3a62e5114b3203075bc7667fd5bbdd43ecc3083ec6f1bc23e1177ce94' 
  AND token = 'BopZy2GE25hrcqGvWSro18vtXm+fQy2RBMJ0ygQzy+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}