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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6025029d3ba90867a54a2ce8ff0bb8f9b76fe4eca97645820bf62e0e27c34ba' 
  AND token = 'TAt9G44MwKrNaSt3bLqFvp2LZIdHA2u0HUlD2eOyloQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}