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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f396e644759b6947efae9ec5d6a68adde4c5a164b6efe09ea99255b43b8efd94' 
  AND token = 'uPvXb9bZwzPR0ixD/XWk5YRv4WFMTCVgfKAmc6dLAKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}