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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3a7495d748a659dad70605a222e28868ade0f10d269b4d66f6ffce4b3f9291' 
  AND token = 'xiOYnnPYNhmNHWGHK1H360wt7HsbWQDIbDpEy6tnm84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}