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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3782093a54e03e6344cad862aa40a616b7aafd91ebf3fca6927e4626db163406' 
  AND token = 'GpiE2ViBZH2pCrUth5f6c8zCuaqLsY01DnSs3P9wQe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}