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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6da20bf37655fa83d35e1ceb20678d9a57a79980e4ac4d17fec17205f79cbac3' 
  AND token = '75DcVj7apBOFk6YsrCltG3tvwmXj9spIlsCiuypm2Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}