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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e07b84d5711755eb3793aa38531672be63431bfb45445979c39ba6e75bb053b' 
  AND token = 'vHqMRCVbDFhAyZg2/CG5p+xEJHexjjD5ayb8+IBOHRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}