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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b32740caa252feaedbf2b380b20b11cbee5d5012cb8982c9aa7263baeab767' 
  AND token = '+8+K3B7YjXYv1/JDhdsf9Q2G6wGiVk8zkkjGWLRREiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}