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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4161ef10e4b5faad7bc18e158a0c57b588c540e93e3e1dc2ef1097b6a34135' 
  AND token = 'kzCn/UzBgEVBmpsNcKUkUdtpc96DfxvWTOjjXHFED2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}